Effect of growth hormone on fatty liver in panhypopituitarism.
نویسندگان
چکیده
A 17 year old boy was admitted because of short stature and hepatomegaly. He was diagnosed with panhypopituitarism and fatty liver. The fatty liver improved, not with hydrocortisone or levothyroxine treatment, but with growth hormone administration. The fatty liver in this patient was attributable to a growth hormone deficient state.
منابع مشابه
Administration of anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody for the treatment of osteoporosis was associated with amelioration of hepatitis in a female patient with growth hormone deficiency: a case report
BACKGROUND Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD). A recent animal study showed that hepatocyte-specific receptor activator of nuclear factor-kappa B (RANK) knockout mice had significantly lower liver fat content compared with control mice concomitant with a decrease in production of inflammatory cytokines such as tumor necrosis factor-α (TN...
متن کاملThe Effect of Eight Weeks of Endurance Training, Growth Hormone Injection and its Lipolytic Fragment (AOD9604) on CK18 and Liver Enzymes of NAFLD-induced Mice Induced by High-fat Diet
Aims: Fatty liver disease and overcoming it is one of the concerns of today's society, so the aim of this study was to investigate the effect of eight weeks of endurance training, growth hormone injection and its lipolytic fragment (AOD9604) on CK18 levels and liver enzymes of mice induced in fatty liver. Materials & Methods: In This experimental study, 28 male mice were, randomly, divided int...
متن کاملEffect of dietary linolenic acid (18:3n–3)/linoleic acid (18:2n–6) ratio on growth performance, tissue fatty acid profile and histological alterations in the liver of juvenile Tor tambroides
This study was conducted to determine optimal ratios of dietary linolenic acid (18:3n-3, LnA) to linoleic acid (18:2n-6, LA) for Tor tambroides. Juveniles were fed three trial diets with different ratios of LnA/LA (0.0, 0.5 and 1.0) for 10 weeks. Another diet contained 100% palm oil, which was similar tothe diet with 0.0 LnA/LA ratio but different in total amounts of C18polyunsaturated fatty ac...
متن کاملEffect of dietary linolenic acid (18:3n–3)/linoleic acid (18:2n–6) ratio on growth performance, tissue fatty acid profile and histological alterations in the liver of juvenile Tor tambroides
This study was conducted to determine optimal ratios of dietary linolenic acid (18:3n-3, LnA) to linoleic acid (18:2n-6, LA) for Tor tambroides. Juveniles were fed three trial diets with different ratios of LnA/LA (0.0, 0.5 and 1.0) for 10 weeks. Another diet contained 100% palm oil, which was similar tothe diet with 0.0 LnA/LA ratio but different in total amounts of C18polyunsaturated fatty ac...
متن کاملThe Effect of Fatty Liver Disease on the Expression of RXFP1 and CTGF Genes in Cardiac Tissue of Wistar Rats
Background & Aims: Performing physical activity and having a healthy body is one of the most essential life needs of people with fatty liver. In recent years, studies have been performed on the relationship between fatty liver and arthrosclerosis. The results of these studies indicate the relationship between the Non-alcoholic fatty liver and arthrosclerosis of coronary artery disease. Non-alco...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 76 6 شماره
صفحات -
تاریخ انتشار 1997